The anti-inflammatory effects of macrolides
نویسندگان
چکیده
منابع مشابه
The anti-inflammatory effects of macrolides.
Erythromycin and its fourteen-member macrolide analogues have attracted attention for their efficacy in bronchial asthma. However, their mechanisms of action remain unclear. We evaluated the effects of the macrolide antibiotics on endothelin-1 (ET-1) expression in normal and transformed human bronchial epithelial cells, one of the sources of this potent bronchoconstrictor important in the patho...
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Macrolides are a group of antibiotics whose activity is ascribable to the presence of the macrolide ring, a large macrocyclic lactone ring, to which one or more deoxy sugars, usually cladinose and desosamine, may be attached. The most commonly used macrolides have 14 (e.g. erythromycin, clarithromycin, roxithromycin) or 15 (e.g. azithromycin) atoms attached to their macrocyclic ring and therefo...
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Objective: Opuntia humifusa (O. humifusa) Raf. has been used for the prevention and treatment of rheumatoid arthritis, inflammation, and cancer. Our study was designed to unveil the anti-nociceptive and anti-inflammatory effects of the methanolic extract of O. humifusa Raf stem (OHS). Material and Methods: The anti-nociceptive effect was measured by hot plate, acetic acid-induced writhing, and...
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Abstract Aims: To investigate the effect of Myrtenol, the active ingredient of Myrtle, on the oxidant and anti-oxidant indices and cytokines in the allergic asthma. Methods: Allergic asthma was induced by ovalbumin (OVA) sensitization and inhalation in four groups of rats; Control, Asthma, Asthma+Dexamethasone and Asthma+Myrtenol. Myrtenol (50mg/kg) or Dexamethasone (2.5mg/kg) was a...
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ژورنال
عنوان ژورنال: Thorax
سال: 1999
ISSN: 0040-6376
DOI: 10.1136/thx.54.2008.s58